肾小球化生Glomerulus Metaplasia · 肾脏 · 泌尿系统 · NTP ntp-0165
诊断要点:Bowman囊的肾小球化生应当诊断并给出严重程度分级。相关链接:肾脏 - 肾小管 - 肥大
病变描述
在小鼠中,Bowman囊的肾小球壁层上皮存在性别二态性。雌性壁层上皮细胞通常呈扁平状(Figure 1),而雄性壁层上皮既可呈立方状也可呈扁平状。在由某些雄激素类化合物给药所致的肾小球化生中,雌性壁层上皮变为立方状,或呈雄性样(Figure 2)。
诊断与分级建议(NTP 共识)
Bowman囊的肾小球化生应当诊断并给出严重程度分级。相关链接:肾脏 - 肾小管 - 肥大
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
In the mouse, sexual dimorphism of the glomerular parietal epithelium of Bowman’s capsule exists. The female parietal epithelial cells are typically flattened ( Figure 1 ) and the male parietalepithelium can be both cuboidal and flattened. In glomerular metaplasia, caused by administration of some androgenic compounds, the female parietal epithelium becomes cuboidal, or male-like ( Figure 2 ).
Recommendation:
Glomerular metaplasia of Bowman’s capsule should be diagnosed and given a severity grade. Related Links: Kidney - Renal Tubule - Hypertrophy
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/kidney/Glomerulus-Metaplasia
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Glomerulus Metaplasia (kidney). LabSmart 中文版:
https://www.labsmart.cn/ntp/kidney-glomerulus-metaplasia.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#kidney-glomerulus-metaplasia