血管扩张Angiectasis · 胰岛 · 内分泌系统 · NTP ntp-0094
诊断要点:出现该改变时应予以诊断并分级。若血管扩张不广泛,严重程度分级通常为极轻微(minimal)。
病变描述
血管扩张(angiectasis)通常表现为形态不规则的扩张腔隙,腔内含有红细胞和/或血浆,内皮细胞衬覆极少。这是一种自发性改变,已知与给药无关,也不因给药而加重。通常一张切片中仅见一个受累的胰岛。红细胞周围也可能伴有含铁血黄素(hemosiderin)色素沉着(Figure 4)。
诊断与分级建议(NTP 共识)
出现该改变时应予以诊断并分级。若血管扩张不广泛,严重程度分级通常为极轻微(minimal)。若在其他组织中观察到血管扩张或相关改变,应在病理学描述中补充相应评论。若存在含铁血黄素,则无需同时诊断色素沉着。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Angiectasis typically involves irregular dilated spaces that contain erythrocytes and/or plasma with a negligible endothelial cell lining. This is a spontaneous change with no known association with, or exacerbation by, treatment. Typically only one affected islet is seen in a section. There may also be hemosiderin pigment along with erythrocytes ( Figure 4 ).
Recommendation:
When present, this change should be diagnosed and graded. A severity grade will most often be minimal if the angiectasis is not widespread. If angiectasis or related changes are observed in other tissues, a comment to this effect should be added to the pathology narrative. If hemosiderin is present, a concurrent diagnosis of pigment is not necessary.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/pancreatic-islets/Angiectasis
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Angiectasis (pancreatic-islets). LabSmart 中文版:
https://www.labsmart.cn/ntp/pancreatic-islets-angiectasis.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#pancreatic-islets-angiectasis