扩张Dilation · 输尿管 · 泌尿系统 · NTP ntp-0201

依据美国国家毒理学计划(NTP)Nonneoplastic Lesion Atlas 整理 · 中文译文与诊断建议 · 仅供科研使用,不用于临床诊断

一句话结论:输尿管扩张(同义词:肾盂积水/输尿管积水,hydroureter)最常与梗阻性病变相关。
诊断要点:输尿管扩张应予以诊断并评定严重程度分级。若输尿管扩张与受试物相关,研究病理学家应描述该病变为单侧还是双侧。

病变描述

输尿管扩张(同义词:肾盂积水/输尿管积水,hydroureter)最常与梗阻性病变相关。肉眼观察时,常可见其与膀胱扩张及肾盂扩张同时存在。该病变可为单侧或双侧(Figure 1)。在大鼠中,先天性病例以右侧更为多见。已培育出具有自发性输尿管积水与肾积水的NON/Shi小鼠品系及SD/cShi大鼠品系,并可诱导其发生肾盂尿路上皮的增殖性病变。

诊断与分级建议(NTP 共识)

输尿管扩张应予以诊断并评定严重程度分级。若输尿管扩张与受试物相关,研究病理学家应描述该病变为单侧还是双侧。

图谱

扩张(输尿管)组织学图谱 1
图 1 · 扩张 · 来源:NTP NNL Atlas

英文原文

展开 NTP 官方英文描述与建议

Comment:
Dilation of the ureter (synonym: hydroureter) is most commonly associated with cases of obstruction. Often it can be seen grossly with dilation of the urinary bladder and renal pelvis. It can be either unilateral or bilateral ( Figure 1 ). In rats, congenital cases are more prevalent on the right side. A strain of mouse (NON/Shi) and a strain of rat (SD/cShi) have been developed that have spontaneous hydroureter and hydronephrosis and can be induced to develop proliferative lesions of the renal pelvic urothelium.

Recommendation:
Dilation of the ureter should be diagnosed and assigned a severity grade. If ureter dilation is treatment related, the study pathologist should describe whether the lesion is unilateral or bilateral.

来源与引用

原始条目:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/ureter/Dilation

图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。

建议引用格式:NTP Nonneoplastic Lesion Atlas. Dilation (ureter). LabSmart 中文版: https://www.labsmart.cn/ntp/ureter-dilation.html

中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#ureter-dilation

囊肿尿路上皮增生异位组织慢性进行性肾病