眼球萎缩Phthisis Bulbi · 眼 · 特殊感觉系统 · NTP ntp-0335
诊断要点：眼球痨应诊断为存在，但不进行严重程度分级。眼部各亚部位的变化不应单独诊断，因为它们已包含在集合性诊断术语“眼球痨”中。
病变描述
眼球痨（phthisis bulbi）（Figure 1、Figure 2、Figure 3、Figure 4）是用于描述“终末期”眼球形态的诊断术语，该形态由多种原因所致的严重损伤引起，例如创伤、炎症、电离辐射或环境光过度暴露，或眶内占位性肿块（如哈德氏腺肿瘤）的物理压迫（Figure 4）。眼球痨的特征是眼球显著皱缩，伴有眼结构的明显移位和结构紊乱。
诊断与分级建议（NTP 共识）
眼球痨应诊断为存在，但不进行严重程度分级。眼部各亚部位的变化不应单独诊断，因为它们已包含在集合性诊断术语“眼球痨”中。如果存在诱发原因（例如异物），应单独诊断，并应在叙述中描述这两种病变之间的关联。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Phthisis bulbi ( Figure 1 , Figure 2 , Figure 3 , and Figure 4 ) is the diagnostic term used for the "end-stage" eye morphology resulting from severe injury from various causes, such as trauma, inflammation, excess exposure to ionizing radiation or ambient light, or physical compression by space-occupying orbital masses, such as neoplasms of the Harderian gland ( Figure 4 ). Phthisis bulbi is characterized by prominent shrinkage of the globe with marked displacement and disorganization of ocular structures.
Recommendation：
Phthisis bulbi should be diagnosed as present without assignment of a severity grade. Changes in the various ocular subtopographies should not be diagnosed separately as they are included in the collective diagnostic term "phthisis bulbi." If an inciting cause (e.g., a foreign body) is present, it should be diagnosed separately, and the association between the two lesions should be described in the narrative.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/PhthisisBulbi
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Phthisis Bulbi (eye). LabSmart 中文版：
https://www.labsmart.cn/ntp/eye-phthisis-bulbi.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#eye-phthisis-bulbi