副脾Accessory Spleen · 脾脏 · 免疫系统 · NTP ntp-0031

依据美国国家毒理学计划(NTP)Nonneoplastic Lesion Atlas 整理 · 中文译文与诊断建议 · 仅供科研使用,不用于临床诊断

一句话结论:副脾(accessory spleen)(Figure 1,箭头)在啮齿类动物中罕见,可能为先天性、脾切除后获得性或创伤性损伤所致。
诊断要点:副脾应予以诊断,但不进行分级。

病变描述

副脾(accessory spleen)(Figure 1,箭头)在啮齿类动物中罕见,可能为先天性、脾切除后获得性或创伤性损伤所致。在腹腔内肉眼观察时,副脾可表现为一个或多个暗红色至黑色结节,表面光滑,直径从不足1毫米到数毫米不等。这些脾组织小结节可见于脾的肠系膜附着处(Figure 1,箭头所指)、胰腺及腹腔其他部位。组织学上,副脾可具有全部或部分脾结构成分,如被膜、小梁、红髓和/或白髓(Figure 2)。

诊断与分级建议(NTP 共识)

副脾应予以诊断,但不进行分级。

图谱

副脾(脾脏)组织学图谱 1
图 1 · 副脾 · 来源:NTP NNL Atlas
副脾(脾脏)组织学图谱 2
图 2 · 副脾 · 来源:NTP NNL Atlas

英文原文

展开 NTP 官方英文描述与建议

Comment:
Accessory spleens ( Figure 1 , arrow) are rare findings in rodents and may be congenital, acquired following splenectomy, or a consequence of traumatic injury. When observed grossly in the peritoneal cavity, an accessory spleen may appear as one or more dark red to black nodules that have a smooth surface and range from less than a millimeter to several millimeters in diameter. These small nodules of splenic tissue have been observed in the mesenteric attachment of the spleen ( Figure 1 , arrowhead), pancreas, and elsewhere in the abdominal cavity. Histologically, accessory spleens may have all or some splenic components, such as the capsule, trabeculae, red pulp, and/or white pulp ( Figure 2 ).

Recommendation:
Accessory spleen should be diagnosed but not graded.

来源与引用

原始条目:https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/AccessorySpleen

图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。

建议引用格式:NTP Nonneoplastic Lesion Atlas. Accessory Spleen (spleen). LabSmart 中文版: https://www.labsmart.cn/ntp/spleen-accessory-spleen.html

中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#spleen-accessory-spleen

充血出血坏死浆细胞增生淀粉样物质淋巴细胞凋亡