淋巴细胞细胞浸润Infiltration Cellular Lymphocyte · 膀胱 · 泌尿系统 · NTP ntp-0193
诊断要点:由于较小的浸润在啮齿类动物膀胱中常见,病理学家对这些浸润设定诊断阈值并不罕见。确定阈值并在整个研究过程中始终如一地维持该阈值是病理学家的责任。
病变描述
细胞浸润,淋巴细胞性,通常表现为局灶性(focal)至多灶性(multifocal)、边界清楚的黏膜下浸润,以淋巴细胞为主(Figure 1、Figure 2)。浸润也可见于血管周围。大多数细胞浸润往往为自发性,见于其他方面正常的膀胱,几乎没有或没有病理学意义。
诊断与分级建议(NTP 共识)
由于较小的浸润在啮齿类动物膀胱中常见,病理学家对这些浸润设定诊断阈值并不罕见。确定阈值并在整个研究过程中始终如一地维持该阈值是病理学家的责任。当作出诊断时,淋巴细胞浸润应给予严重程度评分。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Infiltration cellular, lymphocyte, usually involves a focal to multifocal, well-defined, suburothelial infiltration of predominantly lymphocytes ( Figure 1 and Figure 2 ). Infiltrates can also be seen around vessels. Most cellular infiltrates tend to be spontaneous, in an otherwise normal bladder, and with little or no pathologic significance.
Recommendation:
Since smaller infiltrates are common in rodent bladders, it is not uncommon for pathologists to have a diagnostic threshold for diagnosing these infiltrates. It is the responsibility of the pathologist to determine the threshold and to consistently maintain that threshold throughout the study. When diagnosed, lymphoid infiltrates should be given a severity score.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/urinary-bladder/InfiltrationCellularLymphocyte
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Infiltration Cellular Lymphocyte (urinary-bladder). LabSmart 中文版:
https://www.labsmart.cn/ntp/urinary-bladder-infiltration-cellular-lymphocyte.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#urinary-bladder-infiltration-cellular-lymphocyte