溃疡Ulcer · 膀胱 · 泌尿系统 · NTP ntp-0194
诊断要点:溃疡应予以诊断并给出严重程度分级。炎症和/或再生性增生明显时,应连同溃疡一起诊断,作为病变慢性程度的指标。
病变描述
溃疡可由多种病因引起,例如直接化学暴露,或作为与炎症、结石或肿瘤相关的继发性病变。溃疡通常由尿路上皮糜烂/坏死进展而来,并延伸贯穿尿路上皮全层,导致上皮下出血和炎症(Figure 1、Figure 2)。炎症的严重程度取决于溃疡的大小和慢性程度。急性溃疡可能迅速发生。慢性病例中可观察到再生性增生和/或纤维化。
诊断与分级建议(NTP 共识)
溃疡应予以诊断并给出严重程度分级。炎症和/或再生性增生明显时,应连同溃疡一起诊断,作为病变慢性程度的指标。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Ulcers may result from a number of etiologies, such as direct chemical exposure or as secondary lesions associated with inflammation, calculi, or tumors. Ulcers usually progress from urothelial erosions/necrosis and extend through the width of the urothelium, resulting in subepithelial hemorrhage and inflammation ( Figure 1 and Figure 2 ). The severity of the inflammation depends on the size and the chronicity of the ulcer. Acute ulceration may develop rapidly. Regenerative hyperplasia and/or fibrosis may be observed in chronic cases.
Recommendation:
Ulcers should be diagnosed and given a severity grade. Inflammation and/or regenerative hyperplasia, when significant, should be diagnosed along with ulceration as an indicator of the chronicity of the lesion.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/urinary-bladder/Ulcer
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Ulcer (urinary-bladder). LabSmart 中文版:
https://www.labsmart.cn/ntp/urinary-bladder-ulcer.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#urinary-bladder-ulcer