上皮纤维化Epithelium Fibrosis · 鼻 · 呼吸系统 · NTP ntp-0125
诊断要点：纤维化在鼻腔中是一种不常见的病变，观察到时应予以诊断并赋予严重程度分级。与炎症一样，与纤维化相关的上皮细胞类型应作为部位修饰词记录。
病变描述
纤维化在显微镜下表现为纤维结缔组织数量增加，取代或扩张正常结构。由于纤维化通常是对严重组织损伤的反应，因此常与炎症和/或坏死相关。鼻部固有层中的纤维化（Figure 1；与Figure 2所示的对照相比）不常见。
诊断与分级建议（NTP 共识）
纤维化在鼻腔中是一种不常见的病变，观察到时应予以诊断并赋予严重程度分级。与炎症一样，与纤维化相关的上皮细胞类型应作为部位修饰词记录。其他病变，如上述炎症和增生，应单独诊断。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Fibrosis appears microscopically as an increase in the amount of fibrous connective tissue that either replaces or expands normal structures. Because it is often a response to severe tissue damage, fibrosis is often associated with inflammation and/or necrosis. Fibrosis in the lamina propria of the nose ( Figure 1 ; compare with control shown in Figure 2 ) is uncommon.
Recommendation：
Fibrosis is an uncommon lesion in the nasal cavity and should be diagnosed and assigned a severity grade whenever it is observed. As with inflammation, the epithelial cell type associated with the fibrosis should be recorded as a site modifier. Other lesions, such as the inflammation and hyperplasia noted above, should be diagnosed separately.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/nose/Epithelium-Fibrosis
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Epithelium Fibrosis (nose). LabSmart 中文版：
https://www.labsmart.cn/ntp/nose-epithelium-fibrosis.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#nose-epithelium-fibrosis