异物Foreign Body · 前胃 · 消化系统 · NTP ntp-0210
诊断要点：原发性异物应当诊断，但不进行分级。如果异物引起显著的炎症反应，则异物和炎症均予诊断。
病变描述
毛发或饲料物质可继发于灌胃操作造成的损伤或外源性化学物引起的溃疡，嵌入前胃壁内。在 Figure 1、Figure 2 中，黏膜下层可见一个中央含有毛干（箭头）的小型肉芽肿；其上方黏膜已从先前损伤中愈合。这被认为是对照动物中的一个小型偶发性病变，可能继发于先前的灌胃创伤。
诊断与分级建议（NTP 共识）
原发性异物应当诊断，但不进行分级。如果异物引起显著的炎症反应，则异物和炎症均予诊断。诸如毛发或饲料物质等被被动推入溃疡区域的异物，不应单独诊断，但可在叙述中描述。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Hair or feed material can become embedded in the wall of the forestomach secondary to injury from a gavage procedure or ulceration from xenobiotics. In Figure 1 and Figure 2 , a small granuloma with a central hair shaft (arrow) is in the submucosa; the overlying mucosa has healed from a previous injury. This is considered a small incidental lesion in a control animal that may have occurred secondary to previous gavage trauma.
Recommendation：
A primary foreign body should be diagnosed but not graded. If a foreign body causes a significant inflammatory response, then both the foreign body and inflammation are diagnosed. A foreign body such as hairs or feed material that has been passively pushed into an ulcerated area should not be diagnosed separately but can be described in the narrative.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-forestomach/ForeignBody
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Foreign Body (stomach-forestomach). LabSmart 中文版：
https://www.labsmart.cn/ntp/stomach-forestomach-foreign-body.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#stomach-forestomach-foreign-body